USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P61981 USC-OGP 2-DE database:  P61981 P61981 General information about the entry View entry in simple text format Entry name 1433G_HUMAN Primary accession number P61981 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=14-3-3 protein gamma; AltName: Full=Protein kinase C inhibitor protein 1; Short=KCIP-1; Contains: RecName: Full=14-3-3 protein gamma, N-terminally processed;. Gene name Name=YWHAG Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1268: pI=4.73; Mw=28790 Cross-references UniProtKB/Swiss-Prot P61981; 1433G_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name 1433G_HUMAN Primary accession number P61981 Secondary accession number(s) O70457 P35214 Q6FH52 Q9UDP2 Q9UN99 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 149) Name and origin of the protein Description RecName: Full=14-3-3 protein gamma; AltName: Full=Protein kinase C inhibitor protein 1; Short=KCIP-1; Contains: RecName: Full=14-3-3 protein gamma, N-terminally processed; Gene name Name=YWHAG Encoded on Name=YWHAG Keywords 3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF142498; AAD48408.1; -; mRNA EMBL AB024334; BAA85184.1; -; mRNA EMBL CR541904; CAG46702.1; -; mRNA EMBL CR541925; CAG46723.1; -; mRNA EMBL AC006388; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC020963; AAH20963.1; -; mRNA CCDS CCDS5584.1; -; . RefSeq NP_036611.2; NM_012479.3; . UniGene Hs.744840; -; . PDB 2B05; X-ray; 2.55 A; A/B/C/D/E/F=2-247 PDB 3UZD; X-ray; 1.86 A; A=1-247 PDB 4E2E; X-ray; 2.25 A; A=1-247 PDB 4J6S; X-ray; 3.08 A; A/B/C/D=1-247 PDB 4O46; X-ray; 2.90 A; A/B/C/D/E/F=1-247 PDB 5D3E; X-ray; 2.75 A; A/B/E/F/I/J=1-238 PDBsum 2B05; -; . PDBsum 3UZD; -; . PDBsum 4E2E; -; . PDBsum 4J6S; -; . PDBsum 4O46; -; . PDBsum 5D3E; -; . ProteinModelPortal P61981; -; . SMR P61981; -; . BioGrid 113364; 299; . DIP DIP-33406N; -; . IntAct P61981; 122; . MINT MINT-248956; -; . STRING 9606.ENSP00000306330; -; . BindingDB P61981; -; . ChEMBL CHEMBL1293296; -; . iPTMnet P61981; -; . PhosphoSitePlus P61981; -; . SwissPalm P61981; -; . BioMuta YWHAG; -; . DMDM 48428721; -; . REPRODUCTION-2DPAGE IPI00220642; -; . EPD P61981; -; . MaxQB P61981; -; . PaxDb P61981; -; . PeptideAtlas P61981; -; . PRIDE P61981; -; . TopDownProteomics P61981; -; . DNASU 7532; -; . Ensembl ENST00000307630; ENSP00000306330; ENSG00000170027; . GeneID 7532; -; . KEGG hsa:7532; -; . UCSC uc011kgj.2; human; . CTD 7532; -; . DisGeNET 7532; -; . GeneCards YWHAG; -; . HGNC HGNC:12852; YWHAG; . HPA CAB013274; -; . HPA CAB018389; -; . HPA HPA026918; -; . MIM 605356; gene; . neXtProt NX_P61981; -; . OpenTargets ENSG00000170027; -; . PharmGKB PA37441; -; . eggNOG KOG0841; Eukaryota; . eggNOG COG5040; LUCA; . GeneTree ENSGT00760000119116; -; . HOGENOM HOG000240379; -; . HOVERGEN HBG050423; -; . InParanoid P61981; -; . KO K16198; -; . OMA IKNCGET; -; . OrthoDB EOG091G0VKY; -; . PhylomeDB P61981; -; . TreeFam TF102003; -; . Reactome R-HSA-111447; Activation of BAD and translocation to mitochondria; . Reactome R-HSA-1445148; Translocation of GLUT4 to the plasma membrane; . Reactome R-HSA-2565942; Regulation of PLK1 Activity at G2/M Transition; . Reactome R-HSA-380259; Loss of Nlp from mitotic centrosomes; . Reactome R-HSA-380270; Recruitment of mitotic centrosome proteins and complexes; . Reactome R-HSA-380284; Loss of proteins required for interphase microtubule organization from the centrosome; . Reactome R-HSA-5620912; Anchoring of the basal body to the plasma membrane; . Reactome R-HSA-5625740; RHO GTPases activate PKNs; . Reactome R-HSA-5628897; TP53 Regulates Metabolic Genes; . Reactome R-HSA-75035; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; . Reactome R-HSA-8854518; AURKA Activation by TPX2; . SignaLink P61981; -; . SIGNOR P61981; -; . ChiTaRS YWHAG; human; . EvolutionaryTrace P61981; -; . GeneWiki YWHAG; -; . GenomeRNAi 7532; -; . PRO PR:P61981; -; . Proteomes UP000005640; Chromosome 7; . Bgee ENSG00000170027; -; . CleanEx HS_YWHAG; -; . Genevisible P61981; HS; . GO GO:0030659; C:cytoplasmic vesicle membrane; TAS:Reactome; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005739; C:mitochondrion; IEA:GOC; . GO GO:0043209; C:myelin sheath; IEA:Ensembl; . GO GO:0005159; F:insulin-like growth factor receptor binding; IPI:UniProtKB; . GO GO:0005080; F:protein kinase C binding; IPI:UniProtKB; . GO GO:0008426; F:protein kinase C inhibitor activity; NAS:UniProtKB; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl; . GO GO:0097711; P:ciliary basal body docking; TAS:Reactome; . GO GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome; . GO GO:0061024; P:membrane organization; TAS:Reactome; . GO GO:0006469; P:negative regulation of protein kinase activity; NAS:UniProtKB; . GO GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome; . GO GO:0006605; P:protein targeting; IEA:Ensembl; . GO GO:0045664; P:regulation of neuron differentiation; IMP:UniProtKB; . GO GO:0009966; P:regulation of signal transduction; NAS:UniProtKB; . GO GO:0048167; P:regulation of synaptic plasticity; IMP:UniProtKB; . Gene3D 1.20.190.20; -; 1; . InterPro IPR000308; 14-3-3; . InterPro IPR023409; 14-3-3_CS; . InterPro IPR023410; 14-3-3_domain; . PANTHER PTHR18860; PTHR18860; 1; . Pfam PF00244; 14-3-3; 1; . PIRSF PIRSF000868; 14-3-3; 1; . PRINTS PR00305; 1433ZETA; . SMART SM00101; 14_3_3; 1; . SUPFAM SSF48445; SSF48445; 1; . PROSITE PS00796; 1433_1; 1; . PROSITE PS00797; 1433_2; 1; .

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